Depending on what you start with you will definately have to machine for larger valve seats for the 2.19 and 1.88 sizes. As for porting I think some mild blending and smoothing to improve std flow will be fine. The exhaust side on the BB heads responds well to some improvement. I'm no machinist but any compentent shop should be able to help.
As for compression..10.0 will do the trick..maybe a little more???. Depending on piston configuration and other factors you can use pump hi-test with modest timing. You may have to experiment a little with total advance...not sure if combustion chamber style will impact how much compression you can get away with..but at 10.0 to 10.5, I don't think it will be a major factor. Will check with one of my engine buddys for his thoughts. Most of the aftermarket suppliers like Edelbrock offer their performance heads with some style of open-chamber design. This design is superior to the original closed chamber head for the way the head flows and allows for "better breathing". Some might say that you can even make more horsepower with less compression. This is important if you want to run your car on pump gas...any engine that performs really well, usually has the right combination of parts and technology. hope some of this helps...
wilma